hERG Patch Clamp | NMI TT Pharmaservices

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Electrophysiology

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NMI-TT Contact Person

Dr. Timm Danker

+49 7121 51530 896


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hERG Patch Clamp

Our manual and automated patch clamp assays reveal interactions of compounds with cardiac hERG channels.

  • hERG currents are recorded from stably transfected CHO cells
  • Protocols are available for single dose testing and dose-response curves
  • Throughput according to our customers needs from one compund to "HTS" screening


Effect of Terfenadine application on hERG channel currents in CHO cells
Effect of Terfenadine application on hERG channel currents in CHO cells



Effect of Quinidine application on hERG channel currents in CHO cells
Effect of Quinidine application on hERG channel currents in CHO cells


Effect of Flecainide application on hERG channel currents in CHO cells
Effect of flecainide application on hERG channel currents in CHO cells
   

 

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NMI TT is a subsidiary of NMI