Simoa Ultra-Sensitive Protein Profiling Services | NMI TT Pharmaservices

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Protein Profiling

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NMI-TT Contact Person

Dr. Jens Göpfert

+49 7121 51530 471




Simoa Ultra-Sensitive Protein Profiling Services

Based on a facility with two Quanterix Simoa HD-1 Analyzers and our long-standing experience with this technology, we offer development, validation and screening of Simoa assays in pre-clinical and clinical samples.

Please email us for more information about our Simoa services.

New! Check out our recent publication on development and validation of an ultra-sensitive procalcitonin biomarker assay.

    Background
The Quanterix Simoa ("single molecule array") technology represents the method of choice for all protein profiling applications that require ultra-sensitive detection, due to low abundance of the proteins of interest and/or in case of precious limited samples.

The Simoa platform is based on the isolation of individual immuno-complexes via paramagnetic beads, but otherwise on standard ELISA reagents. By then measuring in femtoliter-sized wells yields a digital readout on the individual bead level, thus increasing the sensitivity of Simoa assays typically by a factor of 100 to 1,000 as compared to conventional assays. At the same time, even multiplexing of up to 10 analytes is feasible.



 

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