hERG Assay
Our manual and automated patch clamp assays reveal interactions of compounds with cardiac hERG channels.
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hERG currents are recorded from stably transfected CHO cells
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Protocols are available for single dose testing and dose-response curves
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Throughput according to our customers needs from one compound to "HTS" screening
Terfenadine effect on hERG channel currents in CHO cells
Quinidine and Flecainide effect on hERG channel currents in CHO cells
Publications
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Danker T. and Möller C. Early identification of hERG liability in drug discovery programs by automated patch clamp. Front Pharmacol. 2014 | Contact an author.