Automated Patch Clamp Services
Meeting the higher throughput demands of ion channel screening and early hERG risk assessment, automated patch clamp plays an important role in drug development as well as in other areas of research.
Based on Sophion’s QPatch technology, combined with our long-standing expertise in ion channel research and automation of electrophysiological assays, we offer high-quality ion channel screening together with careful data analysis and thorough data interpretation.
hERG screening service- Detect hERG-related safety issues at early stages in the drug development process.
Screening on other voltage-gated and ligand-gated targets- Rely on our long-standing expertise in ion channel research and automation of ion channel assays. Please contact us for specific targets and assay development according to your needs.
QPatch outsourcing service- If you have established QPatch assays but limited instrumental capacity our outsourcing service will help you balance the load.
Kramer, J. et. al. Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells. Scientific Reports 2020 | Contact an author.
Ridder, B et. al. A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm. Toxicology and Applied Pharmacology 2020 | Contact an author.
Danker T. and Möller C. Early identification of hERG liability in drug discovery programs by automated patch clamp. Front Pharmacol. 2014 | Contact an author.