Chromobody® Cell Lines

Chromobody® cell lines enable high-content analyses in living cells, thus allowing for time-resolved analyses of biological processes, e.g. of cell cycle. Several Chromobody® cell lines are already available off-the-shelf (see below) and can be purchased from us immediately. Alternatively, we generate custom cell lines based on your needs and with your Chromobody® of interest. Please get in contact!

Lentiviral Actin-Chromobody® cell lines

Cytoskeletal stess fibers in living cells with the Actin-Chromobody®. in untreated (left) vs TGF-β treated A549 cells (right). Scale bar: 50µm

Lentiviral Vimentin-Chromobody® cell lines

Vimentin-Chromobody® in MDCK (left) and HeLa cells (right)

Lentiviral Lamin-Chromobody® cell lines

Nuclear morphology in HeLa cells with the Lamin-Chromobody®

Lentiviral beta-Catenin Chromobody® cell lines

Nuclear translocation assay with β-catenin chromobodies. Time lapse analysis of (from above) untreated cells and upon addition of GSK3β inhibitor, 20 mM LiCl, and 100 nM LiCl.

Lentiviral Cell Cycle Chromobody® cell lines

Detecting the full cell cycle in living cells via the Cell Cycle Chromobody®