Manual Patch Clamp Services
The gold standard manual whole-cell patch clamp is used for compound profiling in:
- Cell lines
- Primary cells
- In-house and commercially available stem cell-derived cells
- Tissue slices
Get routine assays to study drug effects on voltage-gated and ligand-gated ion channels as well as customer-tailored solutions and assay development. For a more detailed discussion on your specific requirements please contact us.
Your advantage is our expertise in electrophysiology, biochemistry, and pharmacology and our knowledge of the functional relevance of ion channel function and dysfunction in a variety of tissues.
Loser, D et. al. Acute effects of the imidacloprid metabolite desnitro-imidacloprid on human nACh receptors relevant for neuronal signaling. Archives of Toxicology 2021 | Contact an author.
Loser, D et. al. Functional alterations by a subgroup neonicotinoid pesticides in human dopaminergic neurons. Archives of Toxicology 2021 | Contact an author.
Loser D et. al. Human neuronal signaling and communication assays to assess functional neurotoxicity. Archives of Toxicology 2021 | Contact an author.